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Interleukin 6 signal transducer pseudogene 1 (IL6STP1) is a processed pseudogene located in the human genome. Unlike the functional interleukin 6 signal transducer (IL6ST/gp130), which mediates signaling for a family of cytokines including interleukin 6 and interleukin 11, IL6STP1 does not code for a functional protein and is not involved in canonical cytokine receptor signaling. Pseudogenes such as IL6STP1 may, in rare cases, regulate expression of the parent gene or related genetic elements via RNA-mediated mechanisms, but there is no experimental evidence indicating any such function for IL6STP1. It is not considered a therapeutic target, nor is it relevant for drug development, biomarker research, or clinical safety[1][3][5][7].\n\nKey clarification: You may be seeking IL6ST (interleukin 6 signal transducer, "gp130"), which is a cell-surface cytokine receptor and bona fide therapeutic target involved in immune signaling and cancer, but IL6STP1 is only a pseudogene of IL6ST[1][7]. If you need information on the true interleukin 6 signal transducer (IL6ST or gp130), please clarify.
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