Interleukin enhancer binding factor 2 pseudogene 1 (ILF2P1)

Interleukin enhancer binding factor 2 pseudogene 1 (ILF2P1) is a **processed pseudogene** related to the functional gene *interleukin enhancer binding factor 2 (ILF2)*[4]. Pseudogenes are non-functional sequences in the genome that arise from protein-coding genes but have lost their protein-coding ability or are otherwise inactive due to mutations or lack of regulatory elements[2]. ILF2P1 does not encode a functional protein and should not be confused with the protein-coding ILF2 gene (Interleukin enhancer-binding factor 2), which is a transcription factor implicated in immune cell function, cancer, and RNA processing[1][3][5]. There is no evidence that ILF2P1 serves as a therapeutic target, encodes a receptor, or directly participates in any biological or disease processes[4]. **Key context:** - Functional studies, therapeutic targeting, and drug interactions refer to ILF2 (and its protein product), not to ILF2P1, which is a non-coding pseudogene[1][3][5]. - Pseudogenes can sometimes be transcribed, and in rare cases may have regulatory roles (such as microRNA sequestration), but there is no evidence ILF2P1 plays such roles[2]. - ILF2P1 appears only as a genomic annotation, not as a gene with known function or disease association. **Summary:** ILF2P1 is a *non-functional pseudogene* corresponding to the ILF2 gene. It is not a therapeutic target, does not encode a receptor, protein, or regulatory RNA with established roles, and should not be considered a valid drug target. The entry is likely included due to confusion with its parent gene ILF2, which is functionally significant, but ILF2P1 itself is not biologically or clinically actionable[1][4].

Other names

interleukin enhancer binding factor 2, 45kDa pseudogeneILF2P1interleukin enhancer binding factor 2 pseudogene 1