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Target intelligence / Profile preview
Interleukin Family Cytokines (ILs)
- Target
- ILs
- Molecular classification
- Cytokine superfamily
01
Overview
The interleukin family (ILs) comprises a large group of cytokines that play central roles in immune system regulation, inflammation, and cell communication. These molecules are produced by various cell types and act primarily as immunomodulators or "secondary messengers" within the immune system. There are nearly 40 different interleukins identified to date. Dysregulation can contribute to chronic inflammatory diseases or autoinflammatory syndromes. Therapeutics targeting specific interleukins or their receptors have been developed for conditions such as rheumatoid arthritis or autoinflammatory disorders.
- Other names
- Interleukins
02
Mechanism of action
Targeting specific interleukins or their receptors
03
Biological functions
ImmunomodulationRegulation of inflammation (pro-inflammatory and anti-inflammatory effects)Cell proliferationCell activationCell differentiationCell migrationCell adhesion
04
Disease associations
Inflammatory diseasesAutoinflammatory syndromes
05
Interacting drugs
Therapeutics targeting specific interleukins or their receptors
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