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Interleukin Inhibitor
- Molecular classification
- Immunosuppressant, Biologic, Monoclonal Antibody, Recombinant Protein
01
Overview
Interleukin inhibitors are a class of immunosuppressive agents that specifically inhibit the action of interleukins, a group of cytokines that regulate immune responses and inflammation. These drugs suppress the signaling pathways that drive inflammation and autoimmunity by blocking the interaction of interleukins with their receptors. While effective in treating autoimmune and inflammatory disorders, they carry the risk of increased infections due to their immunosuppressive action.
- Other names
- IL InhibitorInterleukin AntagonistCytokine Inhibitor (specific to interleukins)
02
Mechanism of action
Blocks the interaction of interleukins with their receptors, inhibiting downstream signaling pathways that lead to immune cell activation and inflammatory mediator release.
03
Biological functions
ImmunomodulationAnti-inflammatorySuppression of cytokine signalingRegulation of immune response
04
Disease associations
Rheumatoid ArthritisPsoriasisAutoimmune DiseasesInflammatory ConditionsJuvenile Idiopathic ArthritisCardiovascular Diseases (under investigation)
05
Safety considerations
Increased risk of infections (including opportunistic infections)Injection site reactionsImmunosuppression
06
Interacting drugs
Anakinra
2 more in the full profile.
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