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Intestinal Copper Absorption
- Molecular classification
- Physiological Process
01
Overview
Intestinal copper absorption is a tightly regulated process involving specific transporters—primarily CTR1 for entry into enterocytes and ATP7A for export into circulation—with adaptive responses based on body needs. Disruption leads to significant clinical syndromes related either to deficiency or overload.
02
Biological functions
Nutrient absorptionMetal homeostasisCopper transport
03
Disease associations
Menkes disease (impaired)Wilson’s disease (indirectly related to homeostasis)
04
Safety considerations
Copper deficiencyCopper toxicity
05
Interacting drugs
Copper supplements
1 more in the full profile.
06
Biomarkers
Serum copper levelsCeruloplasmin levels
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