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Intestinal Lining
- Molecular classification
- Epithelial Tissue, Biological Barrier
01
Overview
The intestinal lining is a single-layered epithelium that forms a protective barrier within the gut. It selectively absorbs nutrients while preventing the passage of harmful substances. Its integrity is crucial for maintaining homeostasis, and disruption can lead to various diseases.
- Other names
- Intestinal EpitheliumMucosal BarrierGut Lining
02
Mechanism of action
The intestinal lining itself doesn't have a mechanism of action. Drugs interact with its components (e.g., epithelial cells, tight junctions, immune cells in the lamina propria) or aim to protect/repair it.
03
Biological functions
Barrier FunctionSelective AbsorptionProtection against Pathogens and ToxinsNutrient AbsorptionWater and Electrolyte TransportImmune Regulation
04
Disease associations
Inflammatory Bowel Disease (IBD)Leaky Gut SyndromeInfectionMalabsorptionAutoimmune Diseases
05
Safety considerations
Increased Intestinal PermeabilityInflammationAutoimmunityMalnutritionDrug Interactions (altered absorption)
06
Interacting drugs
Mesalazine
2 more in the full profile.
07
Biomarkers
ZonulinLipopolysaccharide (LPS)Intestinal Fatty Acid Binding Protein (I-FABP)Calprotectin
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