Target intelligence / Profile preview

Iron absorption (None)

Target: None
Molecular classification: Other (biological process)

Overview

Iron absorption is the process by which dietary iron is taken up by the body, primarily in the duodenum. It involves several steps, including apical uptake, intracellular processing, and basolateral transfer into the bloodstream. Key proteins involved include DMT1, ferroportin, and hephaestin. The process is regulated by systemic and cellular factors, including hepcidin and erythropoietic demand.

Other names: Intestinal iron absorptiondietary iron absorption

Mechanism of action

Enhancing or inhibiting iron absorption through dietary factors or supplements

Biological functions

Nutrient absorptioniron homeostasiserythropoiesis

Disease associations

Anemiairon deficiencyhemochromatosisanemia of chronic disease

Safety considerations

Iron overloadgastrointestinal side effects from supplements

Interacting drugs

Iron supplements

4 more in the full profile.

Biomarkers

Serum ferritintransferrin saturationhemoglobin levels

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