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Intestinal Microbial Community (None)
- Target
- None
- Molecular classification
- Ecosystem, Microbial Community
01
Overview
The intestinal microbial community, often referred to as the gut microbiota or gut microbiome, is a complex and dynamic ecosystem composed primarily of bacteria, but also includes archaea, viruses, fungi, and protozoa. These microorganisms inhabit the gastrointestinal tract and play essential roles in host physiology, metabolism, immunity, and overall health. Alterations in community structure/function have been linked with various diseases including metabolic disorders (obesity/diabetes), inflammatory bowel disease (IBD), neurological conditions, and cancer risk modulation.
- Other names
- Gut MicrobiotaGut MicrobiomeIntestinal Microbiome
02
Mechanism of action
Modulation of microbial composition and function
03
Biological functions
Nutrient metabolismSCFA productionVitamin synthesisImmune modulationPathogen defenseDigestionBile acid metabolism
04
Disease associations
Metabolic disorders (obesity/diabetes)Inflammatory bowel disease (IBD)Neurological conditionsCancer risk modulation
05
Safety considerations
Unintended consequences of microbiome manipulationPotential for pathogen introductionVariability in individual responsesRisk of opportunistic infections in immunocompromised individuals
06
Interacting drugs
Antibiotics
3 more in the full profile.
07
Biomarkers
Specific bacterial species abundanceSCFA levelsMetabolomic profilesDysbiosis indices
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