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Target intelligence / Profile preview
Human Gut Microbiota
- Molecular classification
- Microbiota, Microbial Community
01
Overview
The human gut microbiota is the diverse community of microorganisms residing in the gastrointestinal (GI) tract. This ecosystem includes bacteria, archaea, fungi, viruses, and protozoans. It performs essential functions such as digestion, vitamin synthesis, immune system modulation, and metabolic regulation. Alterations in the gut microbiota have been linked to various diseases.
- Other names
- Gut MicrobiomeIntestinal MicrobiotaGut Flora
02
Mechanism of action
Varied; depends on specific intervention (e.g., antibiotics disrupt microbial balance, probiotics introduce beneficial strains, prebiotics promote growth of specific bacteria, FMT restores diverse community)
03
Biological functions
Digestion & MetabolismVitamin SynthesisImmune System ModulationMetabolic Regulation & SignalingPathogen DefenseFermentation
04
Disease associations
ObesityInflammatory bowel diseaseIncreased infection riskPotentially increased cancer riskDysbiosis-related disorders
05
Safety considerations
Antibiotic resistanceDysbiosisOpportunistic infectionsPotential for adverse effects from probiotics/prebioticsFMT-related risks (e.g., infection transmission)
06
Interacting drugs
Antibiotics
3 more in the full profile.
07
Biomarkers
Fecal microbial composition (e.g., relative abundance of specific taxa)Short-chain fatty acid (SCFA) levelsMetabolomic profilesMarkers of gut barrier integrity
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