Intestinal microbiota composition modulation

Intestinal microbiota composition modulation refers to the deliberate alteration—through diet, supplementation with specific microorganisms such as probiotics, prebiotic intake, or more targeted interventions like fecal microbiota transplantation—of the complex microbial communities residing in the gastrointestinal tract. This process aims to optimize host health by restoring balance within the gut ecosystem. A balanced and diverse gut microbiome is generally associated with positive health outcomes including proper nutrient metabolism and immune function; conversely, imbalances are linked to various diseases such as cardiometabolic disorders and inflammatory conditions. While this concept is central in both research and clinical practice for its therapeutic potential, it does not represent a single molecular target but rather an approach involving multiple species and mechanisms within an ecological system. Note: "Intestinal microbiota composition modulation" is not a discrete molecule/receptor/target but rather describes an intervention strategy affecting a complex community; thus it should be flagged as incorrect for use where molecular targets are required.

Other names

Gut microbiota modulationGut microbiome modulationModulation of intestinal microbiota compositionMicrobiota modulation

Restoration or alteration of microbial community structure and function through dietary intervention, supplementation with live microorganisms, or transplantation techniques