Intestinal toxins

“Intestinal toxins” collectively refer to harmful substances produced or released in the intestinal environment, often as microbial fermentation products or as cell wall components such as lipopolysaccharide (LPS, also called endotoxin). These molecules, which can include endotoxins, enterotoxins, and secondary bile acids, can impair gut barrier function, provoke immune responses, and are linked to a variety of diseases including sepsis, metabolic syndrome, chronic inflammation, and more. Some well-characterized examples are bacterial LPS (endotoxin), cholera toxin, and bacterial secondary bile acids, all of which affect intestinal or systemic physiology by activating immune pathways, triggering inflammation, or causing direct cellular injury[1][5][6]. This category is overly broad and not a specific druggable or molecular entity.

Other names

endotoxinsgut microbial toxinsbacterial toxinsintestinal microbial toxins