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Intraflagellar transport 80 homolog pseudogene

Molecular classification: Other (Pseudogene)

Overview

Intraflagellar transport 80 homolog pseudogene (ENSG00000259619) is a human pseudogene related to the protein-coding gene IFT80, which encodes a component of the IFT-B complex essential for cilia structure and motility. Pseudogenes such as this are segments of DNA resembling protein-coding genes but are typically non-functional due to sequence changes that prevent protein translation. Thus, this pseudogene does not produce a functional protein and is not considered a molecular target for drug development, biomarker discovery, or human disease mechanisms. When referencing functional biology, disease associations, or therapeutics, information should pertain to the protein-coding IFT80 gene, not this pseudogene[2][6].

Other names: LOC100422032intraflagellar transport 80 homolog (Chlamydomonas) pseudogene

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