Target intelligence / Profile preview

Intraocular Fluid

Molecular classification
Fluid, Extracellular fluid
01

Overview

Intraocular fluid encompasses the aqueous and vitreous humors, essential fluids within the eye that maintain intraocular pressure, provide nutrients, remove waste, support optical properties, and preserve the shape of the eyeball. Dysregulation of intraocular fluid dynamics is implicated in several ocular diseases, most notably glaucoma.

Other names
Aqueous HumorVitreous Humor
02

Mechanism of action

Varies depending on the drug and its target within the eye (e.g., reducing aqueous humor production, increasing aqueous humor outflow)

03

Biological functions

Maintenance of intraocular pressureNutrient transportWaste removalLight transmissionMaintenance of eye shapeImmune defense
04

Disease associations

GlaucomaRetinal detachmentOcular hypertensionUveitis
05

Safety considerations

Drug-induced ocular hypertensionDrug-induced uveitisRetinal toxicitySystemic side effects of ocular medications
06

Interacting drugs

Carbonic anhydrase inhibitors

4 more in the full profile.

07

Biomarkers

Intraocular pressure (IOP)Aqueous humor protein levelsVitreous humor composition

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