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Target intelligence / Profile preview
Iridoid Glycoside
- Molecular classification
- Monoterpenoid, Glycoside, Secondary Metabolite
01
Overview
Iridoid glycosides are a class of plant-derived monoterpenoid compounds characterized by a bicyclic cyclopentapyran core structure with one or more sugar moieties attached via a glycosidic bond. They possess diverse pharmacological activities, including anti-inflammatory, antimicrobial, and antioxidant effects, and serve ecological roles in plant defense.
02
Mechanism of action
Cell cycle arrest or apoptosis induction via modulation of PI3K/Akt and ERK1/2-cyclin D1 pathways (some iridoid glycosides)
03
Biological functions
Defense against herbivores and pathogensAntimicrobial activityAnti-inflammatory activityAntioxidant activityHepatoprotective activityImmunostimulant activityNeuroprotective activityHypoglycemic activity
04
Disease associations
InflammationInfectionLiver dysfunctionDigestive disordersCancer (potential)
05
Safety considerations
Potential side effects at high dosesDosage-dependent toxicityNeed for medical supervision with herbal preparations
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