Target intelligence / Profile preview

Iron Ion Transport

Molecular classification
Transporter, Receptor, Enzyme, Hormone
01

Overview

Iron ion transport encompasses the cellular and systemic processes that regulate the uptake, distribution, storage, and excretion of iron ions. This complex network involves various proteins, including transferrin, transferrin receptors, DMT1, ZIP14, STEAP reductases, ferritin, and ferroportin, which work together to maintain iron homeostasis and prevent both deficiency and toxicity.

Other names
Iron metabolismIron homeostasisCellular iron uptakeSystemic iron regulation
02

Mechanism of action

Varies depending on the specific protein/molecule involved; examples include iron supplementation to increase iron levels, iron chelation to remove excess iron, and hepcidin modulation to regulate iron absorption and release.

03

Biological functions

Iron uptakeIron storageIron transportIron regulationHemoglobin synthesisMitochondrial heme productionRedox reactions
04

Disease associations

Iron-deficiency anemiaHemochromatosisAnemia of chronic diseaseNeurodegenerative diseasesInfection
05

Safety considerations

Iron overloadOxidative stressDrug interactionsHepcidin-related side effectsGastrointestinal side effects from iron supplementation
06

Interacting drugs

Iron supplements

3 more in the full profile.

07

Biomarkers

Serum ironTransferrin saturationFerritinHepcidinHemoglobinRed blood cell count

Beyond the preview

Go deeper on Iron Ion Transport.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Full profile access

Explore the programs pursuing this target and their development progress.

  • Drug candidates
  • Developers
  • Development stage

Clinical trials

Full profile access

Follow the clinical studies evaluating therapies directed at this target.

  • Trial design
  • Status
  • Readouts

Competitive landscape

Full profile access

Compare approaches across drug candidates, modalities, and indications.

  • Programs
  • Modalities
  • Indications

Literature & evidence

Full profile access

Investigate the research and source evidence behind target biology and development.

  • Publications
  • Sources
  • Analysis

Patents

Full profile access

Explore patent activity around therapies and technologies addressing this target.

  • Patents
  • Assignees
  • Technologies

Research & analysis

Full profile access

Connect target biology, drug development, and emerging evidence in your research.

  • Biology
  • Development news
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Iron Ion Transport.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call