Target intelligence / Profile preview

Iron Oxide Nanoparticle (IONP)

Target
IONP
Molecular classification
Nanomaterial, Inorganic compound, Metal oxide
01

Overview

Iron oxide nanoparticles are particles of iron oxide, typically magnetite (Fe₃O₄) or maghemite (γ-Fe₂O₃), with diameters ranging from 1 to 100 nanometers. They exhibit superparamagnetic properties, high surface area, and biocompatibility, making them useful in materials science, medicine, and engineering. Common applications include magnetic resonance imaging contrast agents, drug delivery vehicles, hyperthermia therapy, biosensing, and catalysis. Surface modification is crucial for stability and biocompatibility, and various coatings like polymers, lipids, or silica are employed. While generally considered relatively non-toxic compared to other metal-based nanoparticles, potential safety concerns include toxicity dependent on size and coating, biodistribution, and long-term effects.

Other names
Magnetite nanoparticleMaghemite nanoparticleFe3O4 nanoparticleγ-Fe2O3 nanoparticle
02

Biological functions

Drug delivery vehicleContrast agentHyperthermia agentCatalystBiosensing probeGene delivery vectorMagnetic separation agentVaccine adjuvant
03

Disease associations

Cancer (imaging and therapy)Inflammation (imaging and therapy)Infection (imaging and therapy)
04

Safety considerations

Potential toxicity depending on size, coating, and concentrationBiodistribution and clearanceLong-term effects on organsImmunogenicityAggregation

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