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Iron Stores Replenishment
- Molecular classification
- Physiological Process
01
Overview
Iron stores replenishment is the physiological process of restoring iron levels in the body, particularly in cases of iron deficiency or after blood loss. This process is crucial for maintaining adequate hemoglobin synthesis, supporting erythropoiesis (red blood cell production), and ensuring proper cellular function. It involves the absorption, transport, storage, and mobilization of iron, regulated primarily by the hepcidin-ferroportin axis. Supplementation, either oral or intravenous, is often required to replenish depleted stores.
02
Mechanism of action
Supplementation to increase iron levels in the body, either orally or intravenously.
03
Biological functions
Iron homeostasisErythropoiesisOxygen transportCellular respirationDNA synthesis
04
Disease associations
Iron deficiency anemiaAnemia of chronic disease
05
Safety considerations
Gastrointestinal side effects (oral iron)Iron overload (hemochromatosis)Anaphylaxis (intravenous iron)Drug interactionsExacerbation of infections
06
Interacting drugs
Ferrous sulfate
5 more in the full profile.
07
Biomarkers
Serum ferritinTransferrin saturationHemoglobinRed blood cell countMean corpuscular volume (MCV)Total iron-binding capacity (TIBC)
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