Iron-sulfur cluster assembly 1 pseudogene 2 (ISCA1P2)

ISCA1P2 (iron-sulfur cluster assembly 1 pseudogene 2) is a pseudogene in the human genome that is related by sequence similarity to the protein-coding gene ISCA1, which encodes a protein involved in the assembly of iron–sulfur (Fe–S) clusters in mitochondria. As a pseudogene, ISCA1P2 lacks protein-coding capability, arising from gene duplication or retrotransposition events, and is considered non-functional in the context of protein production or therapeutic targeting. It does not code for a functional protein and is therefore not considered a molecular target for therapeutics, biomarkers, or mechanism-of-action studies. It is not associated with physiological or disease-related biological functions, nor is it part of a recognized molecular family such as receptors, enzymes, or transporters. There is no evidence for involvement in human disease, therapeutic intervention, or measurable biomarker status. No disease associations, known aliases beyond "ISCA1P2", or therapeutic relevance are reported. ISCA1P2’s presence in databases reflects its status as a genomic sequence similar to ISCA1, not as a functional gene product. This entry is not suitable as a therapeutic target or biomarker. ISCA1P2 is often included in genomic databases for completeness, but should not be confused with the functional ISCA1 gene/protein.

Other names

ISCA1P2