Iron-sulfur cluster assembly 1 pseudogene 6 (ISCA1P6)

Iron-sulfur cluster assembly 1 pseudogene 6 (ISCA1P6) is classified as a pseudogene in the human genome. Pseudogenes are genomic DNA sequences similar to normal genes but are nonfunctional; they typically arise from duplication or retrotransposition and do not produce functional proteins. ISCA1P6 does not encode a functional protein product and, thus, is not considered a receptor, enzyme, transporter, or other canonical therapeutic target. Its protein-coding counterpart is ISCA1 (Iron-sulfur cluster assembly 1), which is a functional protein involved in mitochondrial Fe–S cluster assembly. However, ISCA1P6 itself has no established biological or disease role, and no drugs are known to interact with it. The entry "ISCA1P6" refers to a pseudogene, not to the functional target "Iron-sulfur cluster assembly 1" (abbreviation: ISCA1). Only ISCA1 (not ISCA1P6) codes for a functional protein involved in iron-sulfur cluster assembly and roles in mitochondrial function, with some evidence for prognostic relevance in cancer. ISCA1P6, as a pseudogene, is not considered a therapeutic target and has no known function, disease role, or drug relevance based on current scientific databases or literature.

Other names

ISCA1P6