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The iron uptake pathway is a complex network of proteins and processes responsible for the absorption, transport, storage, and regulation of iron in the body. It involves intestinal absorption, transferrin-mediated transport in the blood, and cellular uptake via transferrin receptors and other transporters. Dysregulation of this pathway can lead to iron deficiency or overload, contributing to various diseases.
Varies depending on the specific component targeted: * Iron supplements: Replenish iron stores. * Iron chelators: Bind and remove excess iron from the body. * Hepcidin agonists: Reduce iron absorption and release from cells. * Erythropoiesis-stimulating agents (ESAs): Stimulate red blood cell production.
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