ISG20L2 pseudogene 1 (ISG20L2P1)

ISG20L2 pseudogene 1 (ISG20L2P1) is a pseudogene derived from the ancestral gene ISG20L2, which encodes a 3'-5' exoribonuclease involved in ribosome biogenesis and RNA processing[1][2]. Pseudogenes like ISG20L2P1 do not code for functional protein and are generally considered to lack biological function, although rare exceptions exist. The canonical ISG20L2 gene is involved in rRNA processing and may act as a ribosome biogenesis factor involved in 18S and 5.8S pre-rRNA processing, with reported roles in cell cycle and proliferation in certain cancers[2]. However, ISG20L2P1 itself is not a recognized therapeutic, diagnostic, or research target, nor is it an active enzyme, receptor, or protein[1][2]. Key points: - ISG20L2P1 is a pseudogene, not a protein or RNA with known biological activity. - It is named for its orthology to ISG20L2, a functional exoribonuclease implicated in ribosomal RNA maturation and cell proliferation, but does not share those functions. - There is no evidence it serves as a drug target, biomarker, or has any known role in disease. - Entry of "ISG20L2 pseudogene 1" as a target is likely incorrect for therapeutic or pharmacological consideration. If you require structured information specifically about the functional gene (ISG20L2) rather than the pseudogene, further details can be provided, but this record is for a non-functional pseudogene[1][2].

Other names

ISG20L2P1ISG20L2-PS1Interferon stimulated exonuclease gene 20 like 2 pseudogene 1