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ITPR-interacting domain-containing protein 1 (ITPRID1)

Target: ITPRID1
Molecular classification: Other (predicted coiled-coil domain-containing protein; not a classical receptor, enzyme, transporter, or transcription factor)[2][9]

Overview

ITPR-interacting domain-containing protein 1 (ITPRID1) is a human protein encoded by the ITPRID1 gene, also known as CCDC129. It is characterized by the presence of coiled-coil domains. ITPRID1 is predicted to enable signaling receptor binding activity, but its precise molecular function remains largely uncharacterized. Some studies suggest a potential role in apoptosis and neuronal death pathways, possibly acting as a mediator between the tumor suppressor p53 and BAX proteins, but direct evidence for these functions is limited[1][7][8]. Disease associations identified include lung acinar adenocarcinoma and Tn polyagglutination syndrome[2]. There are no known drugs that directly target this protein, and its utility as a biomarker or therapeutic target is currently unsupported by available evidence.

Other names: CCDC129Coiled-coil domain-containing protein 129FLJ38344ITPRID1

Biological functions

Signaling receptor binding (predicted)possible involvement in apoptosispotential mediator in neuronal death pathways through interaction with other proteins

Disease associations

Lung acinar adenocarcinomaTn polyagglutination syndrome

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