Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
ITPR-interacting domain-containing protein 2 (ITPRID2)
- Target
- ITPRID2
- Molecular classification
- Other (Cytosolic actin-binding protein), Located in cytosol, nucleoplasm, and plasma membrane
01
Overview
ITPR-interacting domain-containing protein 2 (ITPRID2) is a cytosolic, actin-binding protein found across multiple subcellular compartments, including the cytosol, nucleoplasm, and plasma membrane[3][6]. It is encoded by the ITPRID2 gene and is involved in binding to actin filaments, likely contributing to cytoskeletal organization, cellular structural integrity, and motility[3][6]. While paralogous to ITPRID1, no confirmed direct involvement with disease or drug targeting exists[3][6]. The protein is also known under several aliases referencing its discovery in connection with KRAS-induced actin interactions and sperm-specific antigens, but its primary function centers on actin filament regulation[1][3][6][8].
- Other names
- Cleavage signal-1 proteinKRAS-induced actin-interacting proteinSperm associated antigen 13CS-1KRAPKIAA1927SPAG13SSFA2mKIAA19275730488C15Rik
02
Mechanism of action
No mechanisms of action for drugs targeting ITPRID2 are currently documented[3][6].
03
Biological functions
Actin filament bindingCytoskeletal organizationPotential roles in cellular structural integrity and motility
04
Disease associations
No direct associations with major disease categories (such as cancer, inflammation, neurodegeneration, etc.) are described in the current data. Literature may exist on KRAS-induced proteins in cancer, but ITPRID2 is not indicated as a validated disease target in the cited sources[3][6][8].
05
Safety considerations
No notable safety concerns or therapeutic challenges reported for this target[3][6].
06
Interacting drugs
No drugs are listed as interacting with ITPRID2[3][6].
07
Biomarkers
Not listed as a biomarker for patient selection or efficacy monitoring in provided sources[3][6].
Beyond the preview
Go deeper on ITPR-interacting domain-containing protein 2 (ITPRID2).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on ITPR-interacting domain-containing protein 2 (ITPRID2).