Target intelligence / Profile preview

Janus kinase and microtubule-interacting protein 3 (JAKMIP3)

Target
JAKMIP3
Molecular classification
Other (microtubule-binding protein), Protein coding gene
01

Overview

Janus kinase and microtubule-interacting protein 3 (JAKMIP3) is a protein coding gene whose product is predicted to enable microtubule binding and kinase binding activity and is localized to the Golgi apparatus and cell membrane. Its aliases reflect historical naming conventions and gene symbols. It shares some sequence similarity with the JAKMIP1 family member but is distinct from recognized Janus kinases (JAK1-3, TYK2), which are established therapeutic targets. To date, there is no evidence supporting JAKMIP3 as a disease-related gene nor any interacting drugs; it is annotated as a structural or trafficking protein with roles potentially relevant to cellular architecture. If you require standardized structured data on JAKMIP3, note that it is not currently considered a therapeutic target, biomarker, or drug target in clinical or research contexts.

Other names
Neuroendocrine long coiled-coil protein 2Neuroendocrine long coiled-coil 2C10orf14C10orf39JAMIP3NECC2FLJ37857KIAA4091bA140A10.5Jakmip36330417G02Rik
02

Biological functions

Kinase bindingMicrotubule bindingLikely roles in intracellular trafficking or cellular structure
03

Disease associations

Other (no established association with major diseases based on current databases; no clear role in cancer, inflammation, or neurological disease)

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