Japanese encephalitis virus E glycoprotein (None)

The Japanese encephalitis virus (JEV) envelope glycoprotein, or E protein, is a structural protein critical for viral infectivity. It mediates both cellular attachment and membrane fusion during viral entry into host cells and is the primary target of neutralizing antibodies. The E protein is a class II fusion protein with three distinct domains, and undergoes conformational changes to facilitate membrane fusion. It is also glycosylated, which can affect its interaction with cellular receptors. As a major antigenic determinant, the E protein is a key component of JEV vaccines.

Other names

JEV E proteinEnvelope glycoprotein EE protein

Neutralization of viral infectivity; prevention of viral entry