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Target intelligence / Profile preview
Joint Synovial Fluid (SF)
- Target
- SF
- Molecular classification
- Body Fluid, Lubricant, Nutrient Medium
01
Overview
Joint synovial fluid is a viscous liquid found within the cavities of synovial joints, serving as a lubricant, shock absorber, and nutrient medium. It is an ultrafiltrate of blood plasma enriched with molecules like hyaluronan and lubricin, produced by the synovial membrane and chondrocytes. Analysis of synovial fluid is clinically relevant for diagnosing various joint diseases based on changes in composition and physical characteristics.
02
Biological functions
LubricationShock AbsorptionNutrient TransportWaste Removal
03
Disease associations
ArthritisJoint InfectionJoint InflammationOsteoarthritisRheumatoid Arthritis
04
Safety considerations
Risk of infection during aspirationBleeding during aspirationPain during aspiration
05
Biomarkers
Hyaluronan concentrationLubricin/PRG4 concentrationTotal protein concentrationWhite blood cell countCrystal presence (e.g., urate, calcium pyrophosphate)
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