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Kallikrein-related peptidase 2 (None)

Target: None
Molecular classification: Enzyme, Serine protease

Overview

Kallikrein-related peptidase 2 (KLK2) is a serine protease with trypsin-like activity, predominantly expressed in prostatic tissue. It plays a role in sperm liquefaction and is overexpressed in prostate cancer, making it a biomarker and potential therapeutic target. Its activity is regulated by zinc ions and endogenous protein inhibitors.

Other names: kallikrein-2hGK-1hK2

Mechanism of action

KLK2 inhibitors

Biological functions

Sperm liquefactionBlood pressure regulationInflammation

Disease associations

Prostate CancerProstate Disease

Biomarkers

KLK2 overexpression in prostate cancer

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