Karyopherin subunit alpha 4 pseudogene 1 (KPNA4P1)

KPNA4 pseudogene 1 (KPNA4P1) is a human pseudogene related to the karyopherin subunit alpha 4 (KPNA4) gene, which encodes a protein involved in nuclear import of other proteins by acting as an adapter for nuclear localization signal (NLS)-containing proteins. However, the pseudogene KPNA4P1 is not protein coding; it does not produce a functional protein product. There is no evidence that KPNA4P1 functions as a receptor, transporter, enzyme, or has any cellular role attributed to therapeutic targets. This distinguishes it from the parent gene KPNA4, which is involved in nuclear transport and has been implicated in cancer biology, but KPNA4P1 itself is non-functional and not targeted by drugs or therapeutic strategies[7]. - is_target is false because KPNA4P1 does not encode an active molecule and is not a recognized therapeutic target. - is_incorrect is true for most drug discovery, receptor, and enzyme target databases, because KPNA4P1 is a pseudogene and is not the correct entry when searching for actionable or druggable protein targets. Confusion may arise if KPNA4P1 is mistaken for the functional KPNA4 protein-coding gene, which has therapeutic implications in cancer[7]. Key distinction: If your query is about the *functional* nuclear import protein, you mean "Karyopherin subunit alpha 4" (KPNA4), not "KPNA4P1" (the pseudogene)[7].

Other names

KPNA4 pseudogene 1KPNA4P1karyopherin subunit alpha 4 pseudogene