Karyopherin subunit beta 1 pseudogene

Karyopherin subunit beta 1 pseudogene is a **pseudogene** related to the protein-coding gene KPNB1 (karyopherin subunit beta 1), which is involved in the nuclear transport of proteins[2][4]. As a pseudogene, ENSG00000231397 does not encode a functional protein, but may retain sequence similarity to its parental gene. Pseudogenes like this can arise via gene duplication or retrotransposition and usually lack the ability to produce a functional protein[3]. Some pseudogenes can regulate gene expression at the RNA level, for example by acting as competitive endogenous RNAs or miRNA sponges, but there is no evidence of therapeutic utility or direct disease involvement for this particular pseudogene[3]. Important Notes: - This entry is often confused with the functional gene **KPNB1**; however, therapeutic interventions and biological functions relate to the protein-coding KPNB1, not its pseudogene. - Pseudogenes are generally not considered conventional drug targets, nor do they act as receptors, enzymes, or transporters. ENSG00000231397, karyopherin beta 1 pseudogene, is a **nonfunctional genomic locus related to KPNB1**, and should not be considered a direct therapeutic target or receptor. Its canonical full name is "karyopherin subunit beta 1 pseudogene".