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Target intelligence / Profile preview
Katanin regulatory subunit B1 like 1 pseudogene 2 (KATNBL1P2)
- Target
- KATNBL1P2
- Molecular classification
- Other (Pseudogene)
01
Overview
Katanin regulatory subunit B1 like 1 pseudogene 2 (KATNBL1P2) is a non-coding, human genomic sequence classified as a pseudogene, related by sequence similarity to functional katanin B1-like genes. Unlike protein-coding genes, KATNBL1P2 does not produce an active protein product and is not implicated as a functional molecule in drug targeting, disease biology, or biomarker applications. While other pseudogenes have sometimes been shown to regulate gene expression by acting as molecular sponges for microRNAs, there are currently no reports of KATNBL1P2 exhibiting such a function[6][2][8]. For context, the functional katanin B1 (KATNB1) is a regulatory subunit of the katanin microtubule-severing complex, involved in cytoskeletal dynamics and cell division, while KATNBL1P2 is a homologous pseudogene without a confirmed role in these or other cellular processes[3][7][5].
- Other names
- KATNBL1P2HGNC:49052NCBI Gene:100130235Ensembl:ENSG00000232857GC01M095118
02
Biological functions
Pseudogenes generally do not encode functional proteins; however, some may participate in regulatory functions by acting as decoys for microRNAs, influencing the expression of their "parent" genes.There is currently no specific biological function reported for KATNBL1P2 itself.
03
Disease associations
No direct disease association or role described for KATNBL1P2. Pseudogenes in general can sometimes be involved in cancer and other diseases through regulatory effects.
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