Target intelligence / Profile preview

KDM5C adjacent non-coding transcript (KANTR)

Target
KANTR
Molecular classification
Other (long non-coding RNA)
01

Overview

KANTR (KDM5C adjacent non-coding transcript) is annotated as a long non-coding RNA gene located on the X chromosome, adjacent to KDM5C. It is sometimes incorrectly referred to as an "integral membrane protein," but available evidence indicates KANTR does not encode a characterized protein product. Instead, it functions primarily as a non-coding transcript, with mutations in its locus in mice causing tremors and spastic movements, suggesting a potential role in neurological development or function. There is no evidence that KANTR is a classical therapeutic target, receptor, enzyme, transporter, or signaling protein[1][6][10][8]. Current gene and protein databases do not list it as a functional membrane protein, and there are no known drug modulators or clear biological mechanisms attributed to its non-coding transcript. Caution: Referencing "KANTR integral membrane protein" as a protein-coding receptor or drug target is misleading and not scientifically supported by current gene/protein annotation resources[1][10][6].

Other names
KANTRLINC01155SpasmKDM5C adjacent transcriptKDM5C adjacent non-coding transcriptlong intergenic non-protein coding RNA 1155 (LINC01155)
02

Biological functions

Other (not clearly defined; suspected role in neurological development or function in mouse model[1][10])
03

Disease associations

Other (suggested role in neurological features; mutation in mice causes tremors and spastic movements, pointing to potential relevance in neurological phenotypes[1])

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