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Keratin, type II cytoskeletal 79 (KRT79)
- Target
- KRT79
- Molecular classification
- Structural protein, Type II keratin, Cytoskeletal protein
01
Overview
Keratin, type II cytoskeletal 79 (KRT79) is an intermediate filament protein belonging to the type II keratin family. It contributes to the formation and maintenance of the structural integrity of epithelial cells, including those in the skin, scalp, and other epithelial tissues. KRT79 is encoded by the KRT79 gene located on human chromosome 12. Mutations or alterations in KRT79 have been associated with diseases such as arthrogryposis multiplex congenita 2, neurogenic type, and white sponge nevus. The protein primarily functions as a structural component and is not known to be a receptor, enzyme, or direct therapeutic target[1][2][3][6][7].
- Other names
- Keratin 79KRT79K6LKB38KRT6LCK-79Keratin-6LK79Cytokeratin-79Keratin-6-likeType-II keratin Kb38Keratin 6Lkeratin, type II cytoskeletal 79cytokeratin-79keratin 79, type IItype-II keratin Kb38
02
Biological functions
Structural support of epithelial cellsMaintenance of epithelial cell integrity
03
Disease associations
Arthrogryposis multiplex congenita 2, neurogenic typeWhite sponge nevus
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