Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Keratin 17 pseudogene 3 (KRT17P3)
- Target
- KRT17P3
- Molecular classification
- Other (Pseudogene)
01
Overview
Keratin 17 pseudogene 3 (KRT17P3) is a processed pseudogene related to the keratin 17 (KRT17) gene, which codes for a cytoskeletal protein important in the structure of skin, hair, and nails[4][1]. Unlike KRT17, KRT17P3 does not encode a functional protein but may act as a regulatory non-coding RNA. Recent research suggests that KRT17P3 might regulate gene networks involved in cancer, specifically contributing to cisplatin resistance in non-small cell lung cancer via interaction with the miR-497-5p/mTOR pathway[5]. KRT17P3 is therefore of research interest for its possible regulatory role in tumor biology, but it is not a conventional therapeutic target such as an enzyme, receptor, transporter, or structural protein[5][8]. There are no established drugs targeting KRT17P3, and it is not currently used as a biomarker.
- Other names
- KRT17P3keratin 17 pseudogene 3
02
Mechanism of action
Potentially acts through RNA-based interactions, e.g. KRT17P3/miR-497-5p/mTOR axis[5]
03
Biological functions
Other (Potential regulatory RNA function)
04
Disease associations
Cancer (possible role in non-small cell lung cancer chemoresistance)
05
Safety considerations
None established (no protein product; not a direct drug target)
06
Interacting drugs
None known (no direct protein product)
07
Biomarkers
None established
Beyond the preview
Go deeper on Keratin 17 pseudogene 3 (KRT17P3).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Keratin 17 pseudogene 3 (KRT17P3).