Target intelligence / Profile preview

Keratin 17 pseudogene 4 (KRT17P4)

Target
KRT17P4
Molecular classification
Other (Pseudogene, not an enzyme/receptor/transcription factor/etc.)
01

Overview

Keratin 17 pseudogene 4 (KRT17P4) is a noncoding pseudogene related to the functional keratin 17 gene (KRT17), a member of the type I intermediate filament protein family that is important for epithelial structure and homeostasis. Unlike KRT17, mutations or expression changes in KRT17P4 are not known to have biological or therapeutic significance. Pseudogenes like KRT17P4 do not produce functional proteins and thus are not pursued as therapeutic targets or used as biomarkers. For information about disease mechanisms, drug interactions, or biological function, the active gene KRT17—not KRT17P4—is relevant. Additional note: If the intended target was the functional protein keratin 17 (KRT17), please refer to it by its correct canonical name "Keratin 17" and abbreviation "KRT17." Otherwise, information about KRT17P4 as a target or receptor is not applicable, as it is not a protein-coding gene[5][1][7].

Other names
Keratin 17 pseudogene 4KRT17P4
02

Biological functions

Other (No known protein or cellular function; nonfunctional gene)
03

Disease associations

Other (No direct association with human disease as an active biomolecule)Note: Mutations in the functional gene KRT17 (not KRT17P4) are linked to diseases such as steatocystoma multiplex and pachyonychia congenita type 2, but these do not involve the pseudogene[5][1].

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