Keratin 18 pseudogene 12 (KRT18P12)

Keratin 18 pseudogene 12 (KRT18P12) is one of many processed pseudogenes generated from the functional keratin 18 gene (KRT18), a type I intermediate filament protein-coding gene[1][3]. While the functional KRT18 gene encodes a protein important for epithelial cell structure and is implicated as a biomarker in various cancers, its numerous pseudogenes—including KRT18P12—are considered nonfunctional genomic elements that do not code for any protein or play any direct biological role. Pseudogenes like KRT18P12 are generally widely dispersed throughout the genome and lack open reading frames, arising as byproducts of gene duplication or retrotransposition. These pseudogenes are not drug targets, do not act as receptors, and are not involved in disease pathogenesis or therapy[1][3].

Not applicable