Keratin 18 pseudogene 18 (KRT18P18)

KRT18P18 (Keratin 18 pseudogene 18) is classified as a pseudogene, a DNA sequence similar to the functional gene for keratin 18 (KRT18) but generally considered non-coding and non-functional. There is no evidence that KRT18P18 is transcribed into protein or plays a direct biological or pathological role. Unlike its coding counterpart, KRT18P18 is not associated with cellular signaling, disease processes, or drug interventions[6]. Clarification regarding confusion with KRT18: - KRT18 (Keratin 18) is a well-characterized intermediate filament protein with diverse roles in tissue integrity, apoptosis, cell signaling, and is a cancer biomarker[1][2][4][7]. - KRT18P18 is not KRT18. KRT18P18 is a pseudogene, and all references to functions, disease roles, or druggability apply to KRT18—the protein-coding gene—not KRT18P18[6][7]. If your query was directed at the functional protein Keratin 18 (abbreviation KRT18), correct the target to "Keratin 18" or "KRT18"—the information for the pseudogene KRT18P18 does not directly apply to the protein or its uses in diagnostics or as a biomarker. No information was found suggesting KRT18P18 is misspelled or non-existent; the reference to KRT18P18 as a pseudogene is correct per genetic databases[6]. However, it is not a therapeutic target and does not participate in biological/molecular pathways or disease.

Other names

KRT18P18Keratin 18 Pseudogene 18[6]