Keratin 18 pseudogene 24 (KRT18P24)

KRT18P24 (keratin 18 pseudogene 24) is one of at least 77 processed pseudogenes in the human genome that are structurally related to the type I keratin K18 gene. Pseudogenes such as KRT18P24 do not encode functional proteins; they typically lack intact reading frames and are generally considered nonfunctional remnants of once-functional genes. These pseudogenes are widely dispersed across the human genome and, unlike their protein-coding counterparts, do not have known roles as therapeutic targets, biomarkers, or disease-associated entities. The functional KRT18 gene itself encodes a major epithelial intermediate filament and is involved in structural cell integrity, but KRT18P24 does not share these biological activities[1][3]. KRT18P24 is not a receptor, enzyme, transporter, or otherwise an actionable therapeutic target. It is a pseudogene, typically considered nonfunctional and not directly involved in any known cellular or disease process[1][3]. There is no evidence that KRT18P24 is involved in disease, acts as a biomarker, interacts with drugs, or presents safety concerns. The listing is not strictly "incorrect" in the sense of nomenclature, but it would be inappropriate to treat it as a therapeutic target or functional protein, so is_incorrect=true in that context.

Other names

KRT18P24