Keratin 18 pseudogene 36 (KRT18P36)

Keratin 18 pseudogene 36 (KRT18P36) is a processed pseudogene, part of the large human keratin gene family. Pseudogenes resemble known protein-coding genes but typically lack the necessary regulatory or coding sequences required to produce functional proteins. KRT18P36 is named based on its homology with the protein-coding keratin 18 (KRT18) gene, which encodes a type I intermediate filament protein found in epithelial tissues[5][1][7]. However, KRT18P36 itself is not known to be transcribed into functional RNA or translated into a protein. Consequently, it is **not considered a druggable target, biomarker, or therapeutic receptor**, and there is no evidence for its involvement in biological processes or disease mechanisms. Its main relevance is as a non-functional genomic sequence, and not as a molecular target or functional gene. Additional context: - The protein-coding gene KRT18 is well-studied and is involved in cellular structure, apoptosis, and is a recognized cancer biomarker[1][3][5]. However, pseudogenes like KRT18P36 do not have these associations. - Pseudogenes are not classified among molecular target categories such as receptor, enzyme, transporter, or transcription factor[7]. - If information on active targets is required, refer to “Keratin 18” or KRT18, not KRT18P36. Conclusion: KRT18P36 is a *pseudogene*, not a valid therapeutic target, and does not serve as a receptor, enzyme, or biomarker. There appears to be nothing actionable or clinically relevant about KRT18P36. If your interest is in active molecular targets, KRT18 (Keratin 18) itself or related keratin family proteins may be relevant[1][3][5][7].

Other names

KRT18P36