Keratin 18 pseudogene 41 (KRT18P41)

Keratin 18 pseudogene 41 (KRT18P41) is classified as a processed pseudogene derived from the keratin 18 gene. Pseudogenes like KRT18P41 do not code for functional proteins and do not serve as therapeutic drug targets[1]. While its parent gene, Keratin 18 (KRT18), is a major epithelial intermediate filament protein with roles in cancer biomarker discovery and cell death processes[2][3], KRT18P41 lacks the intact genetic sequence needed to be expressed as protein and is not implicated in disease or targeted for therapy. There is no evidence to support its utility in patient selection, efficacy monitoring, or as a clinical safety concern. Notably, various pseudogenes for keratins exist throughout the human genome, frequently cataloged for nomenclature purposes, but they are nonfunctional and have no established physiological or pathogenic significance[1].

Other names

KRT18P41