Keratin 18 pseudogene 42 (KRT18P42)

Keratin 18 pseudogene 42 (KRT18P42) is a processed pseudogene derived from the keratin 18 (KRT18) gene. Pseudogenes are genomic DNA sequences similar to known genes but generally nonfunctional due to disabling mutations or incomplete coding regions. KRT18P42 does not encode the keratin 18 protein and is not expressed as a functional protein. There are at least 77 pseudogenes for keratin 18 dispersed throughout the human genome, many named in systematic order. These pseudogenes do not contribute to cellular processes and are not relevant as therapeutic targets, biomarkers, or disease-associated genes[3][7][8]. In summary, Keratin 18 pseudogene 42 (KRT18P42) is not a functional molecule or receptor and is not a therapeutic target. It does not have biological function, disease roles, drug interactions, biomarker status, or safety considerations. The canonical gene product, keratin 18 (KRT18), is a cytoskeletal protein with major biological importance and clinical relevance, but the pseudogene KRT18P42 is not.

Other names

KRT18P42keratin 18 pseudogene 42