Target intelligence / Profile preview

Keratin 18 pseudogene 51 (KRT18P51)

Target
KRT18P51
Molecular classification
Other, Pseudogene (Processed pseudogene of type I keratin family)
01

Overview

Keratin 18 pseudogene 51 (KRT18P51) is one of many processed pseudogenes derived from the type I keratin 18 (KRT18) gene, dispersed throughout the human genome. These pseudogenes do not encode an intact protein and are considered nonfunctional[3][5]. They are distinct from the functional KRT18 gene, which encodes an intermediate filament protein involved in epithelial cell structure and is a biomarker for several cancers, but pseudogenes such as KRT18P51 have no confirmed biological function, role in disease, or involvement with drugs. KRT18P51 should not be confused with the protein-coding KRT18 gene.

Other names
KRT18P51Keratin 18 pseudogene 51
02

Mechanism of action

None (pseudogene; no mechanism of drug action)

03

Biological functions

None directly (pseudogene; does not encode functional protein)
04

Disease associations

None (KRT18 pseudogenes, including KRT18P51, are not implicated in disease; the functional KRT18 gene, not the pseudogene, is a biomarker in various cancers)
05

Safety considerations

None (not used as a target)
06

Interacting drugs

None (no drugs interact with KRT18P51; KRT18 protein is a biomarker, but not a drug target)
07

Biomarkers

None (KRT18 protein is used as a biomarker, but KRT18P51 is not)

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