Keratin 18 pseudogene 52 (KRT18P52)

Keratin 18 pseudogene 52 (KRT18P52) is a pseudogene related to the Keratin 18 gene. Pseudogenes are stretches of DNA that resemble functional genes but are generally considered non-functional because they do not encode proteins or regulatory RNAs at meaningful levels. KRT18P52 does not encode a functional keratin protein, and there is no evidence it serves as a therapeutic target, biomarker, or has a known disease association. All characteristics and disease associations of keratin 18 (KRT18) — such as roles in epithelial cell structure, cancer biomarker functions, and apoptosis — do not apply to KRT18P52, but to the functional KRT18 gene instead[3]. If you are interested in Keratin 18 (KRT18, a genuine protein with many biological and medical roles), refer instead to its canonical gene, not to KRT18P52[3]. The designation “pseudogene” in the name confirms that KRT18P52 is non-coding and not a direct or indirect drug or diagnostic target. No structured data regarding molecular function, therapeutic targeting, interacting drugs, mechanisms of action, biomarkers, or safety issues is associated with KRT18P52 in the biomedical literature or genetic databases[3]. The target KRT18P52 is therefore not a functional or therapeutic target.

Other names

KRT18P52