Keratin 18 pseudogene 56 (KRT18P56)

Keratin 18 pseudogene 56 (KRT18P56) is a member of the large family of human keratin pseudogenes. Pseudogenes are non-coding genomic sequences that are homologous to functional genes but lack protein-coding ability due to mutations, deletions, or insertions[1]. KRT18P56 is related to the canonical keratin 18 gene, which encodes type I intermediate filament protein involved in epithelial cell structure and stress response, but unlike the functional gene, KRT18P56 does not encode a protein and is not known to participate in any biological process, disease mechanism, or serve as a therapeutic target. There is no current scientific basis to consider KRT18P56 an actionable target in research, diagnostics, or therapy[1][6]. If you intended the protein-coding keratin 18 gene (KRT18), this is a different entity and is considered a legitimate therapeutic and diagnostic target[2][3][5]. However, KRT18P56 specifically denotes a pseudogene and does not meet criteria as a molecular target.

Other names

KRT18P56Keratin 18 pseudogene 56

None; does not encode a targetable entity with a mechanism of action.