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Keratin 18 pseudogene 58 (KRT18P58) is a human pseudogene located on chromosome 11 (chr11:5993876-5994995, hg38)[6]. Unlike the protein-coding keratin genes such as KRT18 (which encodes keratin 18, a type I intermediate filament protein important in cellular structure and apoptosis[1][2][3]), KRT18P58 is annotated as a pseudogene and is not known to encode a functional protein or participate in biological processes. There is no scientific evidence that KRT18P58 is involved in disease pathology, biological function, or is a therapeutic target. Most databases and genomics resources list it solely as a pseudogene, not implicated in drug interactions or clinical biomarker panels[6]. If your inquiry intended the active protein keratin 18 (KRT18), refer instead to "Keratin 18," which is a significant marker and therapeutic target in epithelial cell cancers and liver disease[2][4].
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