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Keratin 18 pseudogene 59 (KRT18P59) is one of many processed pseudogenes in the human genome that share sequence similarity with the functional *keratin 18* (KRT18) gene[3][7]. Keratin 18 is an intermediate filament protein important in the cytoskeleton of epithelial cells and is implicated in diverse cellular processes and diseases, but KRT18P59 itself **does not encode a functional protein** and has no known biological activity, disease association, or relevance as a drug target[3][7]. Like other pseudogenes, KRT18P59 is considered nonfunctional and does not participate in biological pathways; it is mainly a remnant of genomic evolutionary processes[3][7]. If you require information on the functional protein **keratin 18 (KRT18)**, which has biomarker utility and clinical relevance, please clarify, as that is a distinct and functional gene/protein[1][2][5].
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