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Keratin 18 pseudogene 60 (KRT18P60) is a non-protein-coding pseudogene in humans, related to the keratin 18 gene family. Pseudogenes like KRT18P60 typically arise from duplication or mutation of functional genes and do not produce functional proteins. KRT18P60 is not known to participate in any biological process, nor is it associated with disease or therapeutic intervention. Functional and disease information often attributed to keratins, such as cell structure, apoptosis, or cancer diagnosis, applies to active keratin proteins (such as KRT18), not pseudogenes like KRT18P60[3][4][5]. While KRT18 (Keratin 18) is a well-characterized cytoskeletal protein expressed in epithelial cells and is widely referenced as a diagnostic and prognostic biomarker in multiple cancers[1][2][5], KRT18P60 lacks protein expression and biological activity. KRT18P60 is not classed as a receptor, enzyme, transporter, transcription factor, or any standard molecular target category[3][4].
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