Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Keratin 18 pseudogene 9 (KRT18P9)
- Target
- KRT18P9
- Molecular classification
- Other (Pseudogene)
01
Overview
Keratin 18 pseudogene 9 (KRT18P9) is a processed pseudogene related to the keratin 18 gene (KRT18), a key intermediate filament protein in epithelial cells[1]. Pseudogenes such as KRT18P9 are generally non-functional remnants of gene duplication or retrotransposition events and do not code for proteins or have a direct biological or pathological function. KRT18P9 is distinct from the functional keratin 18 gene (KRT18), which plays an important role in epithelial cell structure, apoptosis, and is clinically significant as a biomarker in various cancers[2]. There are numerous processed pseudogenes for keratin 18 dispersed throughout the human genome, none of which contain intact reading frames or produce functional protein products[1]. Notes: - If your interest is in the functional cytoskeletal protein relevant to epithelial cell biology or cancer, you likely want to query for keratin 18 (KRT18) rather than KRT18P9. - No therapeutic targeting, mechanism, or biomarker utility is associated with pseudogenes like KRT18P9[1].
- Other names
- bA513I15.2keratin 18 pseudogene 8KRT18P9
02
Mechanism of action
None
03
Biological functions
None (pseudogenes do not encode a functional product)
04
Disease associations
None directly assigned; however, note that its parent functional gene (KRT18) is involved in cancer and apoptosis via cytoskeletal function, but this does not apply to the pseudogene.
Beyond the preview
Go deeper on Keratin 18 pseudogene 9 (KRT18P9).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Keratin 18 pseudogene 9 (KRT18P9).