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Keratin 8 pseudogene
- Molecular classification
- Pseudogene, Other
01
Overview
Keratin 8 pseudogenes are noncoding genomic sequences related to the keratin 8 (KRT8) gene, which encode no functional protein products. Keratin 8 pseudogenes exist as processed and unprocessed copies dispersed across the genome and do not play a direct role in physiology or disease. The functional KRT8 gene encodes a type II intermediate filament protein, essential in epithelial cell structure, but pseudogenes like ENSG00000249766 lack protein-coding potential and are not relevant as therapeutic drug targets[6][7].
- Other names
- Keratin 8, type II pseudogeneK8 pseudogeneKRT8P (not standard, used to designate keratin 8 pseudogenes generically)
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