Keratin 8 pseudogene 12 (KRT8P12)

Keratin 8 pseudogene 12 (KRT8P12), also known as KRT8L2 or keratin 8-like 2, is a processed pseudogene related to the functional keratin 8 gene. It is not a functional protein-coding gene and is not considered a therapeutic target. Keratin 8 pseudogene 12 (KRT8P12) is a processed pseudogene belonging to the keratin gene family, sharing sequence similarity with the functional keratin 8 (KRT8) gene but lacking a coding function. The keratin gene family consists of both functional genes and numerous pseudogenes; KRT8P12 is classified as one of the type II keratin pseudogenes. Processed pseudogenes like KRT8P12 are derived from reverse-transcribed mRNA and are typically nonfunctional, lacking introns and often integration across the genome. There is no evidence that KRT8P12 produces a functional protein or acts as a receptor, enzyme, transporter, or therapeutic target. In summary, KRT8P12 is a nonfunctional, processed pseudogene related to the gene for keratin 8 and is not a druggable or biologically active target.

Other names

KRT8L2keratin 8-like 2