Keratin 8 pseudogene 23 (KRT8P23)

Keratin 8 pseudogene 23 (KRT8P23) is a processed pseudogene related to the KRT8 gene, which encodes keratin 8, a structural protein in simple epithelial cells. Pseudogenes like KRT8P23 are prevalent in the human genome, particularly for keratins 8 and 18, and derive from non-functional copies of coding genes. KRT8P23 does not produce a protein product, has no known biological activity, therapeutic relevance, or use as a biomarker or drug target. It should not be confused with the functional KRT8 or KRT23 genes[6][7][12]. Clarification: There may be confusion with the functional genes KRT8 (Keratin 8)[1][2] and KRT23 (Keratin 23)[4][11], both of which are protein-coding and play roles in cell structure and certain diseases. However, KRT8P23 is explicitly a pseudogene, not a functional gene product. In summary, KRT8P23 is not a protein, therapeutic target, or functional gene. It is a non-coding pseudogene unrelated to current drug targets, biomarkers, or disease mechanisms[6][7][12].

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